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Seizures are repetitive, involuntary body movements that occur when one’s brain is continuously releasing uncontrollable impulses. It is usually an indication that there is an abnormality in the brain functioning or structural form. Patients often are heavily medicated on anti-epileptic drugs. Though many reports becoming treatment-resistant if they are left to progress further.
Traditional seizure treatment does not aim to treat the underlying condition. Mostly, genetically inherited seizures are not curable because no one can replace the inherited genes from the patient. In post-traumatic seizures, patients are supposed to continue on medication for them to live a comfortable life. CBD for Seizures helps in controlling release of neurotransmitters from one nerve to the other thereby making the synapses to work normal making the person be fully relieved.
Cannabis and Drug Resisting Seizures
In cases where the normal anti-epileptic drugs are failing, CBD for seizures can be used to supplement the effectiveness of the medication. Cannabis makes the brain to stop releasing frequent impulses thereby making the person to calm down. Violent seizures are always controllable through therapeutic cannabis, and it can make the person have improved calmness. Many parents whom their kids have been suffering from treatment –resistant seizures can use the CBD for seizures to make them acquire perfect health again.
Mechanism of Action of CBD for Seizures
The exact mechanism through which CBD for seizures works is unclear but it is known to be effective in animals. In a study where dogs were used as the test hosts, it resulted in the calmness of the epileptic dogs. This effect is attributed to the fact that cannabis reduces the breakdown of acetylcholine at the synaptic junction thereby reducing the speed of impulse transfer from one nerve to the other. As a result, there is calmness since the excessive firing of the nerves is stopped. Research is still ongoing, but practical applications have confirmed that CBD for seizures is perfectly working.
The Preferred Dosage
In most applications, the doses of 200mg to 300mg have been known to yield pleasing outcomes because this is the range where most subjects were observed to improve after the initial dose. In people whose seizures are vigorous and frequent, higher doses may be indicated to ensure that they recover quickly. Taking the CBD for seizures should be done with a lot of carefulness because the drug could turn addictive so easily. It helps to relax the brain tissue and neurons, and it might subject the user into a euphoric state.
Before using the drug, proper psychological assessment should be done, the general health of the person should be done, and the frequency and magnitude of epilepsy should also be identified. In so doing, you will have an idea of the dose that you should take in order for you to improve. In children, the dose should be little to avoid getting them addicted to marijuana. Once the neurons and synapses are relaxed, firing in the brain reduces thereby making the person feel relieved.
Charlotte’s Web is named after Charlotte Figi, born October 18, 2006 epileptic seizures brought on by Dravet syndrome after her first dose of medical marijuana at five years of age. Her usage of Charlotte’s Web was first featured in the 2013 CNN documentary “Weed”. Media coverage increased demand for Charlotte’s Web and similar products high in CBD, which has been used to treat epilepsy in toddlers and children. It was originally called “Hippie’s Disappointment” as it was a strain that had high CBD instead of THC., whose story has led to her being described as “the girl who is changing medical marijuana laws across America. Her parents and physicians say she experienced a reduction of her
In 2015 GW Pharmaceutical initiated Phase 3 clinical trials of investigational cannabidiol, Epidiolex, for treatment of two orphan conditions in children – Dravet and Lennox-Gastaut syndromes. GW also received fast track designation from the US FDA for use of the drug candidate to treat newborns with epilepsy
CLINICAL STUDIES: RESOURCES
- CBD for children with Dravet’s and intractable seizures (Video)
- Report of a parent survey of CBD-enriched cannabis use in pediatric treatment-resistant epilepsy
- Medicinal marijuana stops seizures, brings hope to a little girl
- Cannabinoids for epilepsy
- Cannabis, CBD, and epilepsy – From receptors to clinical response
- Chronic administration of CBD to healthy volunteers and epileptic patients
- Seizing an opportunity for the endocannabinoid system
- Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
- Report of a parent survey of cannabidiol-enriched cannabis use in pediatrictreatment-resistant epilepsy
- From the Editors: Cannabidiol and medical marijuana for the treatment of epilepsy
- Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
- Hypnotic and antiepileptic effects of CBD
- The cannabinoids as potential antiepileptics
- Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats
- Pharmacology of cannabinoids in the treatment of epilepsy
- Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection
- Report from a Survey of Parents Regarding the Use of Cannabidiol in Mexican Children with Refractory Epilepsy.
- Could Cannabidiol be a Treatment Option for Intractable Childhood and Adolescent Epilepsy?